Exercise Adherence and Contamination in a Randomized Controlled Trial of Home-Based Walking Program among Patients undergoing Active Cancer Treatment

ID: 201 Exercise Adherence and Contamination in a Randomized Controlled Trial of Home-Based Walking Program among Patients undergoing Active Cancer Treatment Author Information: Authors List: Presenting Author: Jingjing Shang Additional Author: Jennifer Wenzel Presenting Author: Jingjing Shang Address: 4020 Greenmount Dr Wilmington, DE 19810 USA Ph: 302-482-8583 Fax: Email: [email protected] Institution: Additional Author: Jennifer Wenzel Address: 525 North Wolfe Street Baltimore, MD 21205 USA Ph: 410-502-1114 Fax: Email: [email protected] Institution: Abstract InformationInformation Presentation Preference: SNRS Podium Presentation Willing To Submit Poster? Yes Abstract Categories: Interest Group: Health Promotion/ Self-care Thematic Areas: Chronic illness Introduction: Purpose/Aims: The purpose of this research was 1) to determine adherence/contamination rates in a randomized controlled trial (RCT) of home-based walking program among patients on active cancer treatment; 2) to identify predictors of exercise adherence/contamination. Research Questions/Hypotheses: What are the exercise adherence/contamination rates in a RCT among patients on active cancer treatment? What variables predict exercise adherence/contamination in a RCT among patients on active cancer treatment? Method(s): Patients scheduled for chemotherapy or radiation therapy were randomized to usual care (UC) or an exercise program (EX) throughout cancer treatment. The intervention was a brisk, incremental 20-30 minute walk, 5-6 times/week. Subjects in both groups completed a daily activity log measuring exercise activity level and time. Exercise adherence (or contamination) was determined when a subject engaged in more than 60 minute of aerobic activities in 3 session/week for more than 67% of the total prescribed week. Descriptive statistics identified exercise adherence and contamination rates. Hierarchical multiple regression analysis identified predictors of exercise adherence/ contamination. Results: 126 patients completed the study, (EX=68, UC=58). Mean (SD) age of patients was 60.2 (10.6) years. Most patients were diagnosed with prostate (55.6%) and breast (32.5%) cancer. Adherence was 69% in the exercise group, and contamination was 50% in the control group. Marital status was positively related to exercise adherence in the exercise group (p < 0.05), and educational level was positively associated with exercise contamination in the control group (p < 0.05). Discussion: These results suggest that patients with family support are more likely to adhere to exercise prescription, while well-educated patients in the control group are likely to exercise, which contaminates results. Future CRT might stratify subjects based on their marital status and educational levels. Research Completed : Yes Abstract History: NA Financial Disclosure: Have a financial arrangement or affiliation with commercial companies whose products may be mentioned in this material? No FDA Disclosure: Cleared: Yes Non-Exclusive License: Accepted Terms: Yes Submitted By: [email protected]